除了使用hook外，下面的代码也能够在全局捕捉鼠标：(csdn)

dy_2000_abc(芝麻开门)
public class Form1 : System.Windows.Forms.Form,IMessageFilter
{
private System.Windows.Forms.Button button1;
static void Main()
{
Application.Run(new Form1());
}

private void Form1_Load(object sender, System.EventArgs e)
{
Application.AddMessageFilter(this);
}
public bool PreFilterMessage(ref Message msg)
{
if (msg.Msg==0x205)
{
this.button1.Visible=true;
return true;
}
else
if (msg.Msg==0x201)
{
this.button1.Visible=false;
return true;
}
else
return false;
}
}
}